KMID : 1007520020110030324
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Food Science and Biotechnology 2002 Volume.11 No. 3 p.324 ~ p.326
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The Effect of Nico-N Gum on the Metabolism of Nicotine Absorbed by Smoking
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Kim, Ji-Hoon
Park, Dae-Sung/Lee, Hyean-Woo/Sohn, Joon-Hyung/Chang, Sei-Jin/Jeong, Jong-Moon/Kim, Hyun-Won
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Abstract
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Nico-N was treated in the form of chewing gum to 36 healthy male smokers with at least 2 years of smoking history. Urine analysis showed that cotinine concentration of smokers treated with Nico-N increased dose dependently compared to the non-treated control group. Cotinine, a nontoxic metabolite of nicotine, could be removed from the body in urine. Increase of the cotinine production from the smokers treated with Nico-N indicates the detoxification effect of Nico-N against nicotine.
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KEYWORD
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